At the core of the system is ZYGO’s Coherence Scanning Interferometry (CSI) technology which delivers sub-nanometer precision at all magnifications and measures a wide range of surfaces.īartholomeusz continues, “ The selection criteria when choosing the metrology solution that best matched our application requirements were quite stringent. All measurements using the NewView 9000 are non-destructive, fast (improving productivity and process control), and require no sample preparation. The specific metrology tool used by Metronom was the ZYGO NewView 9000 3D optical surface profiler, which makes it simple and quick to measure a wide range of surface types, including smooth, rough, flat, sloped, and stepped.
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We found that in all respects, ZYGO tools gave us what we needed.”Ĭhosen Metrology Solutions DLC Coating Failure We needed to use metrology tools that combined high functionality with ease-of-use, cost-effectiveness, and that were speedy and scalable. It was difficult to measure the depth of laser-cut blind hole features in clear polymers, and fill heights of clear chemistries in clear polymers.
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We had a difficult time measuring the high aspect ratio and surface roughness of the embossed optical micro-structures. In addition, Metronom’s technology is well suited for high-speed, high-volume manufacturing, which presents opportunities for significant cost advantages compared to existing CGM technology.ĭaniel Bartholomeusz, Director of Process Engineering at Metronom says, “Despite, or perhaps because of, the obvious advantages of our CGM technology, there are some manufacturing challenges, and also some challenges specific to metrology.
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This approach allows Metronom to deliver improved accuracy with a higher signal to noise ratio in the tissue, a built-in quality system right at the sensing site plus additional safety and device-prompted calibration that is derived from a differential oxygen measurement, and a CGM solution that does not have interferences with common medications such as acetaminophen that can challenge electro-chemical methods. The oxygen sensitive polymer changes in fluorescence lifetime as the glucose oxidase enzyme consumes glucose and oxygen in a microscopic reaction chamber. At the heart of the technology is a sensor that consists of an oxygen sensitive polymer at the end of an embossed fiber-optic waveguide.
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Metronom Health’s Continuous Glucose Monitor (CGM) is based on opto-enzymatic technology instead of the typical electro-chemical CGMs. Manufacturing and Metrology Challenges Crosshatch flat Metronom also found that ZYGO’s metrology tools were a key enabling technology that helped to drive their product innovation by providing valuable process and component information using data collection that was easily configurable and flexible. When working at a scale that is difficult to image with traditional microscopes, Metronom found that the 3D optical metrology specialist ZYGO was able to provide the clarity that it is looking for, with features like 3D height mapping and resolution capabilities that were more quantitative and deterministic than traditional microscopes. The company is now at a turning point in its short history, leveraging a sharp focus on engineering and R&D for development of a CGM product that supports the needs of users, as well as the people caring for them.ĭuring the development process, Metronom recognized the critical role of metrology in both R&D and production quality control for its CGM.
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Metronom’s proprietary technology is believed to provide very significant improvements over available Continuous Glucose Monitoring (CGM) technologies, in terms of accuracy in the hypo-glycemic range, reliability, user friendliness, with lower pricing to encourage broader adoption and easier insurance coverage. Founded in 2010, Metronom Health is an early-stage medical device company, focusing on developing an innovative, opto-enzymatic continuous blood glucose monitoring technology for people living with diabetes.